Software

EGAD: ultra-fast functional analysis of gene networks
Summary: Evaluating gene networks with respect to known biology is a common task but often a computationally costly one. Many …
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EGAD: ultra-fast functional analysis of gene networks
Using predictive specificity to determine when gene set analysis is biologically meaningful
Gene set analysis, which translates gene lists into enriched functions, is among the most common bioinformatic methods. Yet few would …
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Measuring the wisdom of the crowds in network-based gene function inference
MOTIVATION: Network-based gene function inference methods have proliferated in recent years, but measurable progress remains elusive. …
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Novel therapeutics for coronary artery disease from genome-wide association study data
BACKGROUND: Coronary artery disease (CAD), one of the leading causes of death globally, is influenced by both environmental and genetic …
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Analysis of genome-wide association study data using the protein knowledge base
BACKGROUND: Genome-wide association studies (GWAS) aim to identify causal variants and genes for complex disease by independently …
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Web tools for the prioritization of candidate disease genes
Despite increasing sequencing capacity, genetic disease investigation still frequently results in the identification of loci containing …
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