Genomics

Predictability of human differential gene expression
Differential expression (DE) is commonly used to explore molecular mechanisms of biological conditions. While many studies report …
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Strength of functional signature correlates with effect size in autism
BACKGROUND: Disagreements over genetic signatures associated with disease have been particularly prominent in the field of psychiatric …
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Using predictive specificity to determine when gene set analysis is biologically meaningful
Gene set analysis, which translates gene lists into enriched functions, is among the most common bioinformatic methods. Yet few would …
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