Genetic

Strength of functional signature correlates with effect size in autism
BACKGROUND: Disagreements over genetic signatures associated with disease have been particularly prominent in the field of psychiatric …
Cite DOI
Measuring the wisdom of the crowds in network-based gene function inference
MOTIVATION: Network-based gene function inference methods have proliferated in recent years, but measurable progress remains elusive. …
Cite DOI
Gentrepid V2.0: a web server for candidate disease gene prediction
BACKGROUND: Candidate disease gene prediction is a rapidly developing area of bioinformatics research with the potential to deliver …
Cite DOI
Analysis of genome-wide association study data using the protein knowledge base
BACKGROUND: Genome-wide association studies (GWAS) aim to identify causal variants and genes for complex disease by independently …
Cite DOI
Conditions for the evolution of gene clusters in bacterial genomes
Genes encoding proteins in a common pathway are often found near each other along bacterial chromosomes. Several explanations have been …
Cite DOI
Comparison of automated candidate gene prediction systems using genes implicated in type 2 diabetes by genome-wide association studies
BACKGROUND: Automated candidate gene prediction systems allow geneticists to hone in on disease genes more rapidly by identifying the …
Cite DOI