Gene Expression Profiling

Predictability of human differential gene expression
Differential expression (DE) is commonly used to explore molecular mechanisms of biological conditions. While many studies report …
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Characterizing the replicability of cell types defined by single cell RNA-sequencing data using MetaNeighbor
Single-cell RNA-sequencing (scRNA-seq) technology provides a new avenue to discover and characterize cell types; however, the …
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Characterizing the replicability of cell types defined by single cell RNA-sequencing data using MetaNeighbor
Exploiting single-cell expression to characterize co-expression replicability
BACKGROUND: Co-expression networks have been a useful tool for functional genomics, providing important clues about the cellular and …
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Guidance for RNA-seq co-expression network construction and analysis: safety in numbers
MOTIVATION: RNA-seq co-expression analysis is in its infancy and reasonable practices remain poorly defined. We assessed a variety of …
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